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Principal AI Engineer

Ladders

📍 United States, US0💼 Full-time🕐 6/3/2026
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Role overview

Ladders is hiring for the Principal AI Engineer role in United States, US. It is full-time, Senior level, in the Tech sector. It was posted 6/3/2026.

On TalentyGo you can review this job and apply more effectively: Charlie prepares an ATS-optimized resume and a cover letter tailored to "Principal AI Engineer" at Ladders in about a minute. Before you apply, you can also check how well your profile fits, with a match score based on skills, experience, location and seniority.

Role
Principal AI Engineer
Company
Ladders
Location
United States, US
Work mode
On-site
Employment
Full-time
Seniority
Senior
Sector
Tech
Posted
6/3/2026

Description

For our client, we are seeking a Principal AI Engineer to join the team of a leader in the Healthcare space. This role will lead work at the intersection of data, AI-enabled capabilities, and scalable technology delivery. You will work across engineering, product, operations, and business stakeholders to translate complex requirements into practical technology solutions. The position offers the opportunity to influence architecture, execution quality, and the technology capabilities that enable long-term growth within a healthcare environment. Location: Remote - US based candidates only, no visa sponsorship available Compensation: $160,000 – $200,000 annually Responsibilities Collaborate with product and engineering teams to design AI solutions for clients Develop LLM applications and agentic workflows using Python Work with structured and unstructured clinical trial data Create multi-agent workflows and intelligent process automation solutions Maintain and evaluate AI systems using modern metrics Drive AI project workflows and enhance software platform user experience Educate team members on AI best practices Qualifications Bachelor's or advanced degree in Computer Science or related field; advanced degree preferred Strong hands-on experience building LLM applications in healthcare Deep understanding of modern Deep Learning and Machine Learning techniques Extensive experience with clinical trials data Proficient in Python and AI frameworks, with API and cloud platform familiarity Benefits Opportunity for professional development and continuing education Access to cutting-edge AI technology and frameworks Collaborative work environment with product and engineering teams Ability to contribute to impactful healthcare solutions Flexibility in exploring innovative AI applications Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.

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